POTD: Returning player confusion - skip mobs or not?

[ManuelBravo]

For the most part you can skip most, what you need to focus is on silver chest to get your lights up. Majority of times you will encounter speed runners go with the flow. As advance in floors, your level will go up, so XP you can normally cap around 30-40th floor for sure by 50 so don't worry too much about xp and focus on doing runs faster and learning the items and when to use them.

NOTE: You have the right idea if your going solo, IF your doing solo attempt work best to have all at 99/99