I can tell you from first hand experience that you will have to scale down your settings to almost the bottom with that card. I was running a 6870 on 1920x1200, and only could set to medium settings. If you expand to 3 monitors, you're going to be running 5760x1200 resolution, and if you're running 3d that cuts framerate in half, so you need 60fps non-3d to run at 30fps in 3d. I would highly recommend a second card at minimum, if not going to a gtx 480 or 580.