Also of note is the two men in the Wanderer's Palace Hard Mode quest. They were driven away from their home, not because they're gay, but because they're different races. Fits quite nicely with the tone of Hilda being a crossbreed and therefore shunned.

Eternal Bonding isn't something to point at as the simple defining thing either. It's well known that Adventurers are quirky to say the least. The general populace probably just wave off our interracial marriages as another oddity of the lifestyle.