Alchemist has been quite profitable the last several months. They make luminous fibers that are required for every single ironworks crafter/gatherer gear and dissolvents used in combat gear. But right now most people already have ironworks gear since its been out for so long, and most people don't need the ilvl 250 crafted gear anymore after the release of 255 PotD weapons and ease of getting token gear, so much less profit than before for all crafters. I used to sell 250 weapons for like 5-8 mil each, now they seem to be down to ~750k-1500k, which of course is a lot more reasonable, but darn for a while I was really raking it in lol.