How mine looks like.

The only keys I actually press are 1-5, alt 1-3, q, e, f, c, v, and `. I click everything else. I've been a "clicker" for almost 10 years so I'm perfectly comfortable with this playstyle. The only macro I use on blm is to use aetherial manipulation to my mouseover target.

Nobody can tell you how you should arrange your HUD but you can always look around and see what you want to incorporate. Consider your needs and work from there.

I don't want to contort my left hand too much to hit certain key combinations, but I also don't want to move my right hand away from my mouse, so that's how my configuration came to be. I also used to have my hp/mp/tp bar at the top left corner but later decided it would be more beneficial to keep it closer to where my eyes are focused in a fight (middle of the screen)