I think I would be more pro +DEF if you could put it onto as many spots as you can +HP.

Since only the body and shield can have +DEF equipped again, even though it will help, I don't see it being worth it as it won't be that noticeable. Especially since you take the shield out of the equation when you are tanking as MRD. Personal preference, I suppose.

Although I would be interesting in making a set of all +DEF and all +VIT gear just to see how it compares.