I think SE does care, but they really need a better system to report these players. And probably more manpower.
In my experience, reporting ingame, even with a billion screenshots, doesn't do anything. Sometimes, I'll get a response advising me to report this sort of thing through the website, directly to the Special Task Force (STF). What happens if you don't? Unless I'm feeling cynical, I have no idea.

I'm pretty sure I have gotten at least one player banned through it though. A regular player even, not an RMT. Because I recorded him teleport-hacking a few times over a couple of weeks, uploaded the videos to YouTube each time, and included them in each of my reports. They were indisputable evidence given the game mechanics I was highlighting. The analytics info for each of the videos show 1-2 views from Japan, and since I set the videos to unlisted, I know those views had to have been from someone reading my reports. Within the next few weeks, I stopped seeing his character around. Instead, I saw what was probably an alt running around, and eventually it was renamed to something similar, and the guy leveled and dressed this alt up to be a smaller copy of the original. So I'm pretty sure that -something- happened to his main, whether temp or perma banned.

So have heart. They do seem to care. It probably helps them a lot if you can keep your reports short and concise, and with solid evidence. (And maybe be fluent in Japanese? I managed in English, at least.) Keep trying.

The layout of the lodestone changes once in a while, but currently, go to "Help and Support" > "Customer Service Suggestions & Feedback Bug Report"
and scroll down to the bottom to "Report a case to the Special Task Force".