I find this way to make such a profit for me that i wanted to share with you. Im still new to this but i think ive found the key locations and fish. Any corrections, additions are welcome. Unfortunately i dont mention catch time period since there are many unstabilities.
1) Dravanian Hinterlands -> Thailak River
Illuminati Perch ( easy to catch with brute leech, best for blue scrips for our bait)
Hinterlands Perch (brute leech -> TierIV SKS from desynthesis)
Dravanian Hinterlands -> Upper Thailak River
Scholar Sculpin ( Purse Web Spider, Grade 1 INT dissolvent from desynthesis)
2) Azys Lla -> Alpha Quadrant
Bullwhip (Fiend Worm -> very easy fish for levequest, hq sell like crazy)
Platinum fish ( Fiend Worm -> also very easy to catch along with bullwhip, desynthesizable into Platinum Nugget)
High Allagan Helmet (moochable from platinum fish, provides Allagan wootz nugget)
3) Azys Lla -> The Pappus Tree
Lungfish -> (brute leech -> fished only with clouds, desynthesizable into Grade 1 Vitality dissolvent)
Tiny Axolotl -> (brute leech -> great fish for red scrips, desynthesis provides Opal)
4) Azys Lla -> Hyperstellar Downconverter
Oliphant's Trunk (fiend worm -> fished only with thunder, desynthesizeable into Lightning IV although i find this fish difficult to find) Requires folklore book in order to hook...
5) Sea of Clouds -> The Eddies
Yalm Lobster ( brute leech -> levequest fish=great profit)
Catkiller (brute leech -> CritIV from desynthesis)
6) Sea of Clouds -> Cloudtop
Blue Cloud coral -> ( red baloon -> ingredient for Grade 1 Mind dissolvent + levequest fish=double profit)
7) Sea of Clouds -> Voor Sian Siran
Caiman -> (moochable from bullfrog (100% chance with bladed steel jig), aetherial reduction is a profit of its own)
8) Dravanian Forelands -> The Iron Feast
Thunderbolt Eel -> (brute leech/bladed steel jig -> another great fish for red scrips)
blueclaw shrimp -> (stonefly nymph -> mooch for thunderbolt Eel + levequest fish)
Pipira Pira -> (brute leech/bladed steel jig (fished only on Dust Storms, fog and clouds) -> i hear baked pipira pira is extremely delicious(!) + levequest fish)
9) Dravanian Forelands -> Whilom River
Dravanian Bass (brute leech -> aetherial reduction )
Pipira Pira (again?? use brute leech here for max results)
10) The Churming Mists -> Sohm Al Summit
Pteranodon (giant crane fly -> best of the best for aetherial reduction since its very easy to catch at any weather)
Another method im using is to buy cheap quantities of Hinterlands Perch, Scholar Sculpin,Whiteloom in order to desynthesize them into SkSIV, Intelligence Dissolvent,Porchini respectively. Of course great profit comes for snagging maps either selling or using.