I have 8.

Four of them are DOW / DOM and I use them for ventures like yak milk / dragon blood most of the time. Other times - when necessary for blue scrips / or for the sake of stacking mats that I think are relevant - I can send them on other items (deep tear eyes, etc...)
Two are botanist, and help me keep a continuous incoming flux for culinarian recipes.
One is miner, and I rarely need it, except sometimes for ores.
The last is fisher, I use it mainly for sweetfish, and dravanian bar (perch ? I never know what they're called in english) and desynth them into Skillspeed IV.
iner
I main culinarian, if I were to change anything, it would probably be remove 1 DOW and take another Bota instead. And swap my miner with another Bota as well.

That's not gonna happen, I'm constantly struggling to send them on ventures, because of tokens, and I won't spend another levelling up 1-60.