You won't lose any serious auto attack damage from not facing the enemy for a second or two, don't worry. The auto attack timers are around the same as the GCD, and the timer counts from your last auto attack regardless if you're facing the enemy or not. Even if you lose, at most, one or two auto attacks over the course of an entire fight, that's not going to gimp your DPS.

That said, I don't know how people on keyboard do it. Controller seems so much better to me, but it's just preference combined with your type of keyboard or controller.