It would be nice to see the results of crafting leves reflected in-game. Something like a hamlet defense that involves not just player DoW/DoM but also crafters influencing defenses and NPC effectiveness via crafted gear/consumables. Engines of war supplied by DoL and crafters. The better the defenses, the stronger the enemy force that is drawn in to the battle (like FFXI besieged levels). At some point the enemy wins and you have to start building up the defenses from stage one again.
How about building an airship that could reach Azeroth? Now that would be interesting. Cid!