Here is a simple DRG setup for controller that uses the least amount of buttons and has easy access to critical functions.

First lets set up some macros:

Now go to Character Config> Hotbars> Cross> General and uncheck "Use pethotbar".

Then go to "Set Selection". Uncheck "Auto swift when weapon sheathed/unsheathed".
Then check "Enable customization when weapon is sheathed" and make sure Hotbar 1 and 3 are checked.
After, check "Enable customization when weapon is drawn" and make sure hotbar 1 and 3 are checked.
Now tapping R1 switches between hotbar 1 and 3 and skips the premade pet hotbar!

Next go to Character config> Hotbars> Cross> "Enable expanded controls" and set the (R2+L2) and (L2+R2) both to cross hotbar 2 left

Finally the actual layout, I personally use a Dualshock 4, so your mileage may vary:

Right Trigger(R2) - Cross hotbar 1 Right

Circle: Heavy Thrust
Cross: Impulse Drive
Square: Disembowel
Triangle: Chaos Thrust

Right: Phlebotomise
Down: True Thrust
Left: Vorpal Thrust
Up: Full Thrust

Left Trigger (L2) - Cross hotbar 1 Left

Circle: Jump
Cross: Power Surge
Square: Spineshatter Dive
Triangle: Legsweep

Right: Blood for Blood
Down: Life Surge
Left: Internal Release
Up: Battle Littany

Left + Right Triggers (L2+R2) - Cross hotbar 2 Left

Circle: Fang and Claw
Cross: Gierskogul
Square: Dragonfire Dive
Triangle: Wheeling Thrust

Right: Mercy Stroke
Down: Blood of the Dragon
Left: Strength Potion
Up: Invigorate

Right Trigger (R2) - Crosshotbar 3 Right

Circle: Javelin Toss
Cross: Ring of Thorns
Square: Doom Spike
Triangle: Elusive Jump

Right: Foresight
Down: Second Wind
Left: Keen Flurry
Up: Bloodbath