If you're a casual player, you don't "just" run savage.

Post 2.0 and 3.15 onward relics are designed to use content that literally anyone can complete. As in, it isn't conceivable that a player would not have enough skill to finish a relic.

Endurance, on the other hand... it's designed to be very, very time consuming to make up for the lack of any sort of skill gating. No one can answer if it's worth the tradeoff except you.

To me, it is not worth it.