there is no issues without leeches...you can use instead Adlo, it nullifies the poisonous effect , even against teh last boss in Bray NM you use that one you dont need leech at all and does an excellent job up 4 stacks depending on which tank is affected mostly.

At later stage of course is another story

BTW I am totally against this idea, people want fast runs with all the advantage and just gain tokens to go faster. You want a lower roulette you go with it and with the disadvantage to go back to be a beginner.