Pulling a Blizzard and making special heirloom items, which are only attainable through PvP IIRC, game-breaking by having them equippable from level one and allowing them to level up along with your character.
Don't have heirloom items? You suck, git gud, scrub. /instabootfromduty
--Having the game practically play itself, for those who are exceptionally lazy. I seriously played a F2P MMO that was like this. The AI took control of my character, and I didn't even have to play. Yuck.
--Making the main story take place in raids. Seriously, don't you fucking do it, SE. Blizzard did it, and it sucked. Don't be a Blizzard.
--If you lost experience by dying--actually, nevermind, that'd make the game more interesting.
--GENDERLOCK. Ragnarok Online did this, and male/female privelage won the day. Don't be a Ragnarok Online.
--Cash shop items give you boosts that you couldn't otherwise get unless you paid the $$$. No, no, NO.