Set up a horizontal hotbar over your actual usable hotbar to see OGCDs, long CDs, and buffs (Berserk, Internal Release), and things you want to use on CD (Infuriate, Berserk, Mercy Stroke).

Use R2+L2 hotbar. I have Mercy Stroke, Berserk, Holmgang, Defience, Deliverence, Unchained, Internal Release, and Decimate here. This allows me to be on whatever hotbar and simply press L2 or R2 in conjunction with whatever side of my hotbar on whatever hotbar I am currently using to get to those abilities.

Also always use Mercy Stroke when it is up lol.

Don't use macros for offensive rotations. The only time I really think macros are ok is for some defensive buffs. For example I macro Foresight and Bloodbath together. They both are 90 second CD and it is the only way I will really use Foresight lol.