I would try the following macro/rotation for 1 star synths. It will require some food but should be achievable with base crafting stats (718 Craftsmanship, 695 control). CP required is 431 with all hasty touches, 449 with one basic touch, and 467 with two basic touches (this is WITH food).



The macro for this is three parts and really long:
/ac "Maker's Mark" <me> <wait.2>
/ac "Comfort Zone" <me> <wait.2>
/ac "Flawless Synthesis" <me> <wait.3>
/ac "Flawless Synthesis" <me> <wait.3>
/ac "Flawless Synthesis" <me> <wait.3>
/ac "Flawless Synthesis" <me> <wait.3>
/ac "Flawless Synthesis" <me> <wait.3>
/ac "Flawless Synthesis" <me> <wait.3>
/ac "Flawless Synthesis" <me> <wait.3>
/ac "Flawless Synthesis" <me> <wait.3>
/ac "Flawless Synthesis" <me> <wait.3>
/ac "Flawless Synthesis" <me> <wait.3>
/ac "Flawless Synthesis" <me> <wait.3>
/ac "Comfort Zone" <me> <wait.2>
/echo Macro #1 complete <se.1>

/ac "Inner Quiet" <me> <wait.2>
/ac "Steady Hand II" <me> <wait.2>
/ac "Waste Not II" <me> <wait.2>
/ac "Hasty Touch" <me> <wait.3>
/ac "Hasty Touch" <me> <wait.3>
/ac "Hasty Touch" <me> <wait.3>
/ac "Hasty Touch" <me> <wait.3>
/ac "Steady Hand II" <me> <wait.2>
/ac "Hasty Touch" <me> <wait.3>
/ac "Hasty Touch" <me> <wait.3>
/ac "Hasty Touch" <me> <wait.3>
/ac "Hasty Touch" <me> <wait.3>
/ac "Hasty Touch" <me> <wait.3>
/ac "Careful Synthesis II" <me> <wait.3>
/echo Macro #2 complete <se.1>

/ac "Master's Mend II" <me> <wait.3>
/ac "Steady Hand II" <me> <wait.2>
/ac "Hasty Touch" <me> <wait.3>
/ac "Hasty Touch" <me> <wait.3>
/ac "Great Strides" <me> <wait.2>
/ac "Ingenuity II" <me> <wait.2>
/ac "Byregot's Blessing" <me> <wait.3>
/ac "Careful Synthesis II" <me> <wait.3>
/ac "Careful Synthesis II" <me> <wait.3>
/ac "Careful Synthesis II" <me> <wait.3>
/ac "Careful Synthesis II" <me> <wait.3>
/echo Macro #3 complete <se.14>