Win 10, no idea.. but Win 7 x64 absolutely..

nvidia 347.52
3 way SLI GTX Titans
5760x1080 DX11 at high
full screen mode, window mode works too but at a lower quality due to the way SLI works.

I had to manually create a SLI profile for FFXIV Heavensward as this driver version doesn't have one, v353.30 has but has other issues with DX11 not displaying properly.

so to answer: yes, SE and NVidia does work on SLI for this game, however is win 10 and drivers on their top priority? who knows :P