Trying to set those twisted fragments in one direction ...
Celestial noise detected, but maybe I'm unsuspected?
Standing to give to reason, turning the key for defense ...
Transmissions begun completing, setup to >BREACH and >RESET.
Interference here can be either referring to something like the cosmic microwave background radiation (i.e. the static you see when you turn on an old TV) or some sort of interference run by an aetheric being. Both possibilities could refer to Hydaelyn, though the second could refer to another Primal. It might not be unreasonable to assume that Alexander's original summoning 3 summers prior may have failed in large part due to Bahamut, who would have been competing to consume large amounts of Aether. However this whole line also should be talking about the Enigma Codex.

Trying to set those twisted fragments up in one direction, would imply they're trying to interpret the data encoded within. Celestial Noise would most likely be referring to Hyadaelyn here, though it could be referring to the codex serving as Alexander's brain, and being unaware that the Goblins are controlling him.