Since the in-game suggestion box lets you leave messages longer than in here, I'm just going to summarize what I suggested.

For in-game events, including tells, friends sign on/off, MB sales, legendary/unspoiled pops, and other important notifications which can happen while AFK because of RL, add option to toggle audio triggers for events. For example, I don't like the tell audio since it's an aggrevance with RMT. Node farming, if I have to step away because of RL, I would appreciate the game playing a sound then, as well as when I sell something so I can restock or make new purchases, and/or when friends sign on so I can message them. Considering how much of the game is waiting for stuff to happen - and with ever-tighter restrictions with the new HW content (looking your way, barely 3 minute unspoiled nodes), having short windows of opportunity - I think this would go a long way into making the game more versatile and easier to handle while doing your day-to-day life stuff.