While I'm sure there are some people with issues under Windows10 (probably the same percentile that has issues under other systems) the game does in fact work just fine in Windows10 under normal conditions. Issues some people are experiencing are highly likely a result of driver issues or misconfigured software.

As always with a new Windows version if you want it to work at its best, you should do a clean install to ensure there isn't any old software around causing incompatibilities, the only thing required on a clean install, are some additional DirectX files that does not ship with Windows10 by default. You do NOT need to reinstall the entire game, but you can run the installer to make it update those DirectX files its missing, after which the game starts and runs the same as normal under both DirectX 9 & 11.