Accuracy requirements significally upped for all turns.
A1: Both bosses show up at start, have more HP and hit harder, there are more adds, and more rockets drop at the same time in different locations. Possibly some new mechanics.
A2: Overwhelming 8th and 9th enemy waves added, 3 bombs drop at the same time.
A3: Two tether pairs, more often knockbacks, 2-3 twisters, slimes have much more HP.
A4: 4-5 orb chains, healer debuff lasts longer and ticks harder, possibly 4 legs instead of 2, two mobs inside quarantine.

Whats your new mechanics predictions?