/woman-hands-here
I have a tough time using KB-M on games because it hurts my hands.
I used the same logitech controller for about 7 years.
When 2.0 came out it really didn't like my controller so i shed a tear and bought something that was compatible at the time - an (official) X-Box360 wired USB for PC.
While it took some getting used to (Dpad in different spot), I really appreciate the more ergonomic feel (the way I can hold the controller more softly even in /seriousraidmode)
Not to mention its plug and play, no worrying about desyncing or any other BS that controllers with programs might give you.
I can't say it will be the same for your wife, because I have longer hands/fingers. But that's how it is for me ^^.