I have this all the time,gtx 970. Whenever i try to enter an instance crash to desktop, zone into ishgard from 2.0 area bang crash to desktop. I gave up and just went back to directx 9 and havent had a crash since. Seems to be a problem mainly with 900 series cards and directx 11, there is a few people talking about it in the technical forums but not any word yet from SE about it.