I don't use Second Wind. It costs too much stamina. I just used a combination of Cure and Sacrifice, then Cure II and Sac II when I got it, and now I have Sac III which is godly for soloing.

Also get shockspikes, that is another very helpful soloing skill.

Honestly, Second Wind costs too much stamina and doesn't heal enough. It's best to just take PGL up to rank 20 to get Prime Conditioning, then maybe to rank 30 to get Accomplice if you are going to tank.