Shots Fired: A Machinist Guide

[Cascadi]

Precasting both is unrealistic. It's hard enough to get the raid group to wait for Ninjitsu CD to come back around after pre-casting Huton.

It's also a waste of your 6th ammo.

Precasting only QR just short of its CD is much cleaner & provides greater DPS.

Opening with Split Shot for a free early proc then following into Hot Shot > Lead Shot also makes for much smoother early buffing (very important for Reload prep).

Opener should be:

15s-ish out QR > Split > 2xbuff > Hot Shot > 2xbuff > Lead Shot > Slug Shot > ¿Clean Shot? > buff + Reload > Rotation (Reassemble Clean Shot).

Reload Rotation is:

Split>Slug>Clean>Split>Slug>QR>Split>Clean>Slug>¿Clean?

Buff also implies Blank+Head Graze/Supressive Fire casting where appropriate.

¿? = if procured.

Yuri's right on all points too...

Again, it is not a waste of your ammo at all... like how you mentioned your starter with QR, my opener is the same thing except instead of 1 ammo, you have access to 5 at the beginning.
This results in this in your format:
20s-ish out QR > Split > 2x Buff > Hot Shot > 2x Buff > Lead Shot > Slug > Split > Buff > Clean > Reload > Slug > Split > Clean > Slug > Split > Clean > QR > Slug > Clean
4x Split
4x Slug
4x Clean

vs

15s-ish out QR > Split > 2x Buff > Hot Shot > 2x Buff > Lead Shot > Slug > ¿Clean? > Buff + Reload > Split > Slug > Clean > Split > Slug > QR > Split > Clean > Slug > ¿Clean?
4x Split
4x Slug
2x Clean + 2x ¿Clean?
¿? = if procured.