One helpful thing I didn't learn for a long time: you can set R3 or L3 to "Assist." Go to the system preferences menu and then to the setting for the controls. I used R3 as Assist and then found another preference (I think it was in character preferences somewhere) to do 1st person if I zoom in far enough on the camera instead.

What Assist does is it changes your target to whatever your current target is targeting. It is great for switching back and forth between boss and tank, especially if they are not in your party (Fates, helping another Alliance tank, etc). For WHM, using Assist may eliminate the need for <tt> macros, although there it is still nice to not switch targets at all.