Most of the debuffs are not worth your time removing because any debuff under 10 seconds that isn't paralyze or silence, doesn't affect the player's ability to do their job.

That said, esuna/leeches is best used to remove poison stacks, not single instances of poison. The game has both, and the latter is pointless to remove since they all tick down at the same rate, where as the single stack of X poison is literately the poison stacking due to multiple casts, so you can remove when it you can't heal through it.