First, the config:
evga x58 microatx board, intel i7 950 cpu, 6gb ram, gtx 280, 9800gt, ocz 700w psu.

Played fine for ages. Occational issues/lockups, restart always worked fine, fiddling witht he drivers, etc. system doesn't like one of hte monitors and won't detect it's default resolution, so I have to switch monitor ports to get it to detect. Now as of yesterday, it locks up when am in game. That is to say,t he screen artifacts, turns neat green/purple colors, and function ceases. Restart and it's fine. I have evga precision up and gpu is fine on temp and only at 95% load. CPU is below temp as well, and only at 10% load. My guess is psu, I've tried different drivers from 260 all the way to 280.

System lists kernal-power event id 41, which i'm guessing is because i hit the reset button. Application logs show faults, sometimes it's ffxivgame.exe, sometimes it's explorer, nvcplui, mpc-hc64, it's all over the place. I'm at a loss, and open to suggestion.