Sleigh's:
B2 > M > B > Swift + Fester > Shadowflare > Rouse + Spur > R2 > Pot > R2 > RS + Pain > R2 > Fester + DWT > R2 > Enkindle + Aether > R2 > 3D > R2 > Fester > R3 > R2 > Deathflare
** I've been using a slightly modified version of this that I feel has been giving me the most return.
So I've tried this, using fester before DWT won't let you get another fester especially with a 15 sec pot which means you have to fester as you enter DWT and the pot duration needs to be higher than 10 secs. Realistically this opener is great for not clipping but I still feel it's lacking in terms of maximum dps burst. As soon as you have your pot pop'd you literally have 15 secs until deathflare and there are 2 R2s before DWT is activated, so that's 2 GCDs off the DWT buff timer. I can't comprehend the loss no matter how many times I try. Maybe you can give me some insight, please?

Avalen's:
Bio II -> Miasma -> Bio -> Swiftcast + Fester > Shadowflare -> Rouse/Spur > Ruin II > Ruin II > Raging Strikes + PainFlare -> Ruin II -> X-Pot + Fester / DWT -> Ruin II -> Tri - Disaster + Enkindle -> Ruin II -> Aetherflow +Contagion -> Ruin III -> Ruin III -> Ruin II -> Fester -> Deathflare -> Ruin II -> Shadowflare ->....
Now avalen's one is somewhat better for me because the pot is activated as DWT goes off so DWT duration is almost matching the Pot's with only one fester. This opener is realistic and I can kind of comprehend it. The alignment of CDs is flowing nicely.

The opener I've decided to go with even though I feel it can improve:

Bio 2 -> Miasma -> Bio -> Painflare -> Fester -> R2 -> Swiftcast -> Rouse -> Shadowflare -> Spur -> Raging -> R2 -> Painflare -> Aetherflow -> R2 -> Pot -> R2 [Bio is dropping] -> Enkindle [delay] -> DWT -> Tri-D -> Fester [10-11 secs left on pot] -> R3 -> R3 -> R3/R2 -> Fester [1-2 secs left on pot] -> Deathflare [before pot ends]

Now what I want is to squeeze 2 festers in my raging (20)+pot (15) +DWT (15) because it's that good especially when it crits, also I get more time to R3s. I want to setup a timeline for this opener to enhance the efficiency. Contagion can be squeezed anywhere because it can be activated during a GCD of Ruin 3. My best burst was a crit on festers 5K and one 7k crit on deathflare without a pot/food or a nin. i189 with the i200 weapon. Any suggestions/advice? :c