I've only recently starting to take my crafting seriously, so I leveled TAN, BSM and ALC to get maker's muse preserve and fulfillment. My questions is, whether or not there is a best time to use these abilities or should I just select them as they appear? Should I wait till the orb starts blinking before using preserve or should I just use it right off the bat if it's available? If I'm just using a standard synth, is Maker's Muse more preferable than fulfillment, or does it matter? At this point I'm mostly grinding, but if there's a difference when one if crafting items for sale, I'd like to know it also. Any help on this matter would be greatly appreciated.