I've had sound issues rarely all the way back since beta. That early storyline mission in ul'dah for example where you're defending a woman...first time I did tha the music wouldnt play for me. When I did a much later storyline quest (the really cool battle cutscene in the sahagin area with various npcs) sound effects weren't playing for good parts of it, like no gunshot sounds.

It always feels like each time a new patch comes out, various issues that always existed suddenly act way worse until the next patch. When 2.4 came out my game kept going stuttery then crashing maybe 50% of the time I teleported somewhere.