My settings is:
Multisampling: 8xQ MSAA
General Drawing Quality: 9
Background quality: 5
Shadow Details: Highest
Texture quality: High
Texture filtering: Highest

My gfx card is the Asus Radeon HD 6970 with 2 nice big fans and its just massive using 3 slots of space on the motherboard

If altering settings dont work, i would recommend you check your internet provider. We were supposed to have a 10mb line. But only get 7,5 since we live a bit away from the server, but before I checked the Wifi and router setup, I was having a line of just 2,95mb.

So if someone is using both Wifi and hardwired connections, that may cause enough to get internet packet data loss. I also told my ISP to run a test on my line to see if anyone has managed to sneak his way onto my Wifi network.

Hope any of this helps.