not possible, while still using skills.
this is a pretty open ended question. what skill level are you? 1star? 4 star?
if you are 1 star, the method for collecting as many unspoiled nodes so far, keeping in mind this is constant uptimes, would be (taken from http://www.reddit.com/r/ffxiv/commen...ring_rotation/ )
Eorzea Time (ET) 1:00 - 4:00
Location: East Shroud (21,26)
Item: Cocoon (4)
Skills: Toll (300GP) + +5% gathering (50GP) + +10%HQ (100GP)
Location: Coerthas (27,19)
Item: Dark ore (3)
Skills: +5% gathering (50GP) + +30%HQ (300GP)
Location: Mordona
Item: Clusters (2-7)
Skills: +5% gathering (50GP) + Crystals+2 (400GP)
Eorzea Time (ET) 5:00 - 8:00
Location: Mordona
Item: Clusters (2-7)
Skills: +5% gathering (50GP) + Crystals+2 (400GP)
Location: Costa
Item: Honey Lemon seed (1)
Skills: none
Run around gathering mandrake seeds till enough GP then
Location: West Thanalan (19,28)
Item: GE Soil (8) + Clusters (4)
Skills: +5% gathering (50GP) + Crystals+2 (400GP)
Eorzea Time (ET) 9:00 - 12:00
Location: Drybone (29,24)
Item: Gold ore (6)
Skills: Toll (300GP) + +5% gathering (50GP) + +10%HQ (100GP)
Location: Coerthas (31,14)
Item: Spruce logs (6)
Skills: +5% gathering (50GP) + +30%HQ (300GP)
Location: Mordona
Item: Clusters (2-7)
Skills: +5% gathering (50GP) + Crystals+2 (400GP)
Eorzea Time (ET) 13:00 - 16:00
Location: Mordona
Item: Clusters (2-7)
Skills: +5% gathering (50GP) + Crystals+2 (400GP)
Location: Drybone (12, 16)
Item: Black truffles (7)
Skills: +5% gathering (50GP) + +30%HQ (300GP)
Location: Wineport (17,28)
Item: Tomato seed (1), tomato (3)
Skills: +5% gathering (50GP) + +30%HQ (300GP)
Eorzea Time (ET) 17:00 - 20:00
Location: Wineport (17,34)
Item: Salt (1)
Skills: +5% gathering (50GP) + +30%HQ (300GP)
Location: Mordona
Item: Clusters (2-7)
Skills: +5% gathering (50GP) + Crystals+2 (400GP)
Eorzea Time (ET) 19:00 - 0:00
Location: Summerfort (23,26)
Item: G3 soil (8) + Clusters (3)
Skills: +5% gathering (50GP) + Crystals+2 (400GP)
Location: Mordona
Item: Clusters (2-7)
Skills: +5% gathering (50GP) + Crystals+2 (400GP)
that said, there is great variety in both skill rotations, and whether these are particularly what you want or not. for instance, I never get the truffles or the honey lemons, because I don't really use them ever.