To Touch with Death or not to Touch with Death. (Mnk question)

[SunnyHirose]

ToD is on the order of 0.4~1% more DPS if you use it whenever it is about to fall off, a difference which can easily be overshadowed by crits and stuff.

Demolish is supposed to fall off under conventional usage (even if it's about half a second). It's technically a DoT, but is best understood as 2 GCDs of an 18-GCD loop because the ticks are so strong that any opportunity you get to clip it cuts into its potency quite a bit. At that point where you see ToD and Demolish both about to fall off, the optimal thing to do depends entirely on what's best to do for ToD, because whatever you do isn't going to affect the loop one bit (except when oGCD buffs are factored in, then it's a little more complicated I guess).

ToD before using PB is weaker than doing it after, since you're only sacrificing ~3 ticks to get 27% GL3, 10% Twin Snakes (those two alone more than make up for the lost ticks), and possibly 10% Blood for Blood, >10% Internal Release, >10% potion on the first one, to say nothing of these things buffing auto-attacks as well. Not always (KotL bosses make me miss the first stack refresh if I try this ), just as a general thing.