People seemed to have liked the math before, so let's run through a few things. We'll start out with 2 simple builds focused on end-game gear. We won't use the relic weapons as currently you can't upgrade your relic weapon to 135. So we'll be using the Dreadwyrm Cane with a base of 82 Magic Damage. Race wise I will be using a Lalafell - Dunesfolk (myself) for the stats. Your Mind/Piety may be slightly higher or lower then what you see, but it should only be off by a small margin.
The two builds in question will be as follows:
Determination - Going strictly for every piece of gear that adds determination with the exception of NOT using the ilvl 120 and ilvl 130 ring together (because MND is the primary stat we want, with determination being 2nd of course). So both ilvl 130 rings will be used.
Piety - All gear that has piety on it, again with the exception of the rings. 1 Pie = 8 mana (roughly rounded)
Please note this also assumes the best food used possible, as will be shown in each link at the very bottom.
Determination Build
http://ffxiv.ariyala.com/P8BL
Mind - 664
Det - 333
Pie - 413
Mana - 4850+
SSpeed - 506
Crit - 428 (11.39%)
Cure 1 - 1540 (Average Heal)
Piety Build
http://ffxiv.ariyala.com/P8BO
Mind - 664
Det - 243
Pie - 530
Mana - 5790+
SSpeed - 450
Crit - 459 (13.56%)
Cure 1 - 1500 (Average Heal)
Conclusion
If you want to sacrifice a little over 900 mana, you can pump out an extra 40 HP (on average) with Cure 1. This is using the best food for both, which happens to be the same exact food, and a 4 star synth (doubtful most people are willing to spend the money to have this made). I'm not saying one build is better then the other, all I'm doing is providing the raw data. Each person will have to decide for themselves if they want more mana, or bigger heals (or a hybrid of both).

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