There's really no reason not to remove them with how "useful" they are in regards to mechanics;

- They can't be very specific to actions. You can't word a macro to "click off" a debuff from what I've seen, nor can you macro something that a button would function differently under different circumstances (like holding another key, or a sequence of skills)

-You can't macro them to split seconds, only whole seconds. This kills the effectiveness to use them in combos.

-People who spam macros...well we're getting into individuals who abuse things.