It does, slightly. If you must have a BL+ME+GCD macro, confine it to 1 button you don't use often (like Straight Shot) and just spam that between GCDs. It's better than having it on everything but only slightly worse than missing a BL/ME proc due to not seeing it. You can of course just get better at noticing when they're up (adjusting your UI to make these more noticeable), but I know a good handful of macro BRDs who all do very well up to and including Final Coil.

The DPS increase from going unmacroed isn't that huge (FOR BRD; for other DPS it's no question, do not macro), and it depends on you executing to the fullest 95% of the time to actually achieve the better results.