Quote Originally Posted by Panteleon View Post
I still don't understand why people don't lead with Miasma instead of Bio II. When you go Miasma -> Bio II -> Bio -> Bane, then the Miasma and Bio drop off at essentially the same time (assuming you start reapplying in the same M/B II/B I fashion once Bio I hits 5sec on the counter). Therefore, it simplifies the reapplication and Bane-ing process for multiple targets and allows you not to miss a tick of damage across multiple targets.

So... when I'm planning to Bane, I always lead with Miasma.

Even when I'm doing a single target rotation, I always lead with Miasma. Between Festers and reapplication of the DoTs as the time comes (in matched groups; i.e. Miasma/Bio I at the same time followed variably by Festers, restarted Bio II's, then again restarted Miasma/Bio I), you end up with all DoT's dropping at the same time after the third cycle, meaning you cleanly restart your applications.

Is there something I'm missing about the value of leading with Bio II?
Thats the thing, you don't want them to fall at the same time since they always have to be rolling. Your DoTs should never be falling off when starting with Bio II and there are enough things to do to make sure you have zero downtime during a whole encounter with your DoTs having a near 100% uptime (minus certain Boss phases where they disappear/are untargetable).