Generally speaking ( assuming you don't have insane skill speed for no good reason ) you can fit 5 skills on the global cool-down in between your first dot applications. If you keep this in mind you will never have to check to see when your dots will fall off. The macro in the above post will help you if your not to good at weaving in your cds but i would highly suggest you start practicing at low lvls without them so by the time your 50 you wont rely on a macro. Also i disagree with the start of his endgame rotation, it isn't usually a good idea to blow them all off the back like that but instead weave them in.