For doing HQ 2 star synths, probably the 3 most important crafts are Weaver at level 50, carpenter 50 and Alchemist 50. I'd recommend weaver first because Careful Synthesis 2 is very very nice. Carpenter has one of the most important skills for HQing, bryegot's blessing. And Alc has Comfort Zone for gear that's under melded for CP. Culinarian to 37 for Steady Hand 2 is a very good idea also.
As you're gearing and skilling up, another skill to take consideration of would be Tricks of the Trade (20 CP back for a Good quality node), though I find myself never using it lately, although I hear it's good for 3 star synths if your melds aren't perfect
For 2 star synths, the minimum melds you need would be 347 Craft, 340 Control, and about 370+ CP with food. Always use HQ equipment for these melds as the stat caps are higher, and do your level 50 class quests for the i55 tool.
And as for materia, ilvl 1-29 equipment gives tier 1, 30-44 gives Higher chance for Tier 2 with chance for tier 1, 45-50(need clerification) gives tier 3 with a chance for tier 2 and an even smaller chance for tier 4, and 55+ is higher chance for tier 4 with a chance of getting tier 3s. From my experience i70 always gives tier 4 materia
Finally for making money: I'm looking into 3 star weaver synths for an attempt to make some money that way, but I've been doing 2 star CUL synths in the mean time to get me some pocket change so I can gear up my Weaver (currently 358/348/344 while using the Artisan's Specs and not using Artisan's Needle)
One HUGE thing I'll recommend to you right now is: For your Armourer or Leatherworker, try gearing one of those up enough for 2 star synths, make 5 of the philo tome items (Darksteel Ingot for ARM or Hard Hippogryph Leather for LTW) and get the Artisan's Spectacles. They're the best hat you can get atm and give 3 Control more then a fully melded i55 hat. The best part is they can be used for ALL DoH jobs. The best accessories you can get also share this property so it makes gearing other DoH jobs easier


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