I generally keep Eos on Obey since her cooldowns are more powerful when controlled.

For Selene it depends on what I'm doing and how lazy I'm feeling. One thing I like about having Selene on Sic is that she'll cycle her speed buffs every 30 seconds on her own, however that prevents you from directing her heals and properly utilizing her silence. I tend to forget to hit her speed buffs on Obey and 30 second macros don't work well enough since hitting a different macro will stop it.