My fastest speed run (first two bosses only) was 5:12 from instance start to robot dead. Went War/Whm/Brd/Blm. Pull to base of ramp, holy/flare/whatever bards do, benediction the tank when he needs a heal, continue damage. Once everything is dead, grab the key, pull everything to first boss room and lock it all out. Dps the boss as quickly as possible, stopping to heal when needed (my best run needed only 2x Med 2 and 2x Regen for first boss). After boss, pull next three groups, gather them, zerg them down. For the second boss, dps like mad; we only needed 1x med 2+ Cure 2+regen.
It will get faster as folks gear up; the biggest thing is knowing when to bail out for your healer and when to use externals. I used E4E on trash pulls and virus on bosses.