This is happening quite a bit to me on PS3, as well. Whether I teleport, zone transition or go from game to cutscene, if there's a loading screen it'll quite often hang, forcing me to quit to the XMB. If not, then it most certainly hangs for much, MUCH longer than it should.
2.2 really broke this game, which is sad, 'cuz you'd think there would have been pre-testing to make sure this went smoothly.