Practice, practice, practice. Force yourself to do the things you have the most trouble with. Also make sure your keybindings for abilities and movement don't interfere with each other. The default action keys (1 through = ) and the default movement keys are terrible together. There's no way you can run and hit = at the same time. So rebind your actions to keys you can actually use.

Personally, I use Legacy camera controls and strafing, and only ever use the mouse to turn. All my action keys are either keys clustered around the movement keys, with modifiers (alt and shift) for more.