I always thought that the game crashing on alt-tab was intentional to prevent botters since the days of FFXI. I actually ripped off my Windows keys back in the early FFXI days to stop accidentally hitting them and crashing in the middle of a battle and pissing off my static.

That said, I run a dual monitor setup right now. I set my 42" LED TV as the main monitor and basically just plop down on my couch with a controller and wireless keyboard. My 24" LED monitor sits at my desk and just displays Ventrilo so I can see who's talking. I also have my system information on it (CPU, Temp, RAM, GPU etc.). The controller is what sets the whole thing up though. It means I can't accidentally click out to the other monitor and crash the game. Works pretty well.