We each have that place that we eagerly anticipate in the game let's list a few
Hellsguard Isles: I must be one of the few people who enjoyed the volcanic regions in FFXI, be it the isle released with Zilart or the Aht Urghan areas as a whole. Given the back story of the Hellsguard as keeping the denizens of the underworld at bay I think this would be a perfect location for a certain 3 headed hound to make his appearance.
Original Sea Wolf territories: This is a no-brainer, they based them on ancient viking raiders why not take showcase the northern lands not as a frozen wasteland but a dangerous tundra with foreboding forests large megafauna and such.
feel free to add your own ideas