Gear set/macro changes not saved in game.

[Nekodar]

I have had this issue as well. If I create a new gear set, say for weaver, it doesn't save the new one and when I log in next the gear set reverts to my old one which has almost all of my gear missing. This has happened since the 2.16 patch.

Are you on PS3 like the OP?

Have you tried deleting one set and recreating it?