But then the quests wouldn't fit the script that nearly all the other quests have:

Get me X number of things.
This guy/girl doesn't like you for [Reasons] and or your guild leader doesn't like you for [Reasons]
Work with this guy/girl that doesn't like you for [Reasons] and bring me X number of things.
Make peace with guy/girl that doesn't like you for [Reasons] and bring me X number of special things.
You are a winner, number one. Everyone loves you.