VS. most single bosses I just use it whenever it's up, I have 5 Wrath/Infuriate, and I'm not low on health/about to take a big hit. Also, as everyone else said, Infuriate -> Unchained -> Berserk is ridiculous for hate... but honestly you don't really need to do that anymore. It's good for snap threat to do Unchained -> Tomahawk -> Berserk -> Tomahawk/BB combo, though. For ADDs I've been sticking to SS (if I have 5 Wrath from previous pull) -> Berserk -> OP x2/3/4 (depending on how many mobs). Honestly just raw OP holds insane threat now, so if it's not ADDs on a boss I'd just stick to OP + Bloodbath.


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